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Medicine Box Challenge: 2/3 - 2. How often should you take doses of medicine?
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1. What happens when you take a medicine?
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3. Getting the right dose
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Representional graph depicting water levels in a bath and medicine in the blood
How well a drug works and how long it acts for depends on how much there is in the blood stream (the concentration in the blood). This concentration varies with time depending on how quickly it gets from the stomach and how quickly your body gets rid of it. It is just like trying to fill a bath with a leaking plug – as some goes in part of it runs out.

Imagine what happens to the level of water in the bath if you gently pour one whole bucket of water in. The level goes up quickly but then starts to drop as the water leaks out. It is the same with levels of drug in your blood. Just think of the bucket of water being a tablet of drug.

Different medicines have different blood level profiles. These profiles depend upon their relative rates of take-up from the stomach and loss through the kidneys and liver.